Blackhead Product Testing | Comedogenicity Study
Clinical testing to assess whether ingredients contribute to or reduce blackhead formation (comedones) in real-world in vivo conditions.
What you can expect from Anti-Blackhead Clinical Testing:
A comedogenicity study typically involves a 30-subject panel, where participants receive up to 12 semi-occlusive patch applications containing up to four test formulations, alongside a positive control (lanolin). A fifth site is left untreated to act as a negative control.
The study duration is typically 4 to 8 weeks, depending on the protocol design.
Test products are applied under controlled patch conditions throughout the study period. In the final week, a surface biopsy technique is used to assess comedone formation. This involves applying a glass slide with cyanoacrylate adhesive to the test site. Once removed, the adhesive lifts surface material, including comedones and corneocytes, for analysis.
Slides are then examined under low-power magnification (approximately 50x), allowing for quantitative assessment by counting comedones per defined surface area.
This provides a robust, objective measure of comedogenic potential across test and control sites.
Claims Substantiated
- Non-comedogenic
- Reduces the appearance of blackheads
- Helps improve skin clarity
- Supports pore-cleansing claims